Transcriptomics Pain Signatures Database
This website allows you to search for specific genes and pathways in the Transcriptomics Pain Signatures Database (TPSDB), which is a database of differentially expressed genes and pathways derived from hundreds of comparisons in multiple publicly available datasets of various pain phenotypes in multiple species to help you test your hypothesis, learn about conditions in which your favorable genes and pathways are differentially expressed, and more.
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Type your gene or pathway into the search bar, then use the advanced search options to reduce your search. Pain phenotype will either take all the phenotypes, or a specific one of your choice. The other options can have multiple selections.
Species:
?
The species that the contrast is done in.
Mmus: Mouse
Rnor: Rat
Hsap: Human
Sscr: Pig
Hsap
Mmus
Rnor
Sscr
Contrast:
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The main subject of the comparison:
PAIN: Comparison of pain assay
TIME: Comparison of time points in each pain assay
SEX: Comparison of sexes
SITE: Comparison of pain sites
CELL: Comparison of cell types
DIET: Comparison of diet
MUT: Comparison of mutated genome
Pain Phenotype
Time
Sex
Cell Type
Sex:
?
The sex of the species used in the study:
M: Males only
F: Females only
MF: Males and females combined
Unknown: not mentioned in the study
MF
F
M
Unknown
Method:
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Sequencing method used in the study:
HTS: High throughput sequencing
ARRAY: Microarray
HTS
ARRAY
Pain Category:
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Study pain phenotypes:
IP: Inflammatory pain
NP: Neuropathic pain
OTH: Other pain types
IP
NP
OTH
Pain Phenotype:
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Pain assay used in the study:
AA Arthralgia
ACR Acrylamide-treated
BCP Bone cancer pain
BURN Burn injury
CAIA Collagen antibody-induced arthritis
CCD Chronic compression of the DRG
CCI Chronic constriction injury
CFA Complete Freund's adjuvant
CGN Carrageenan-treated
CIPN Chemotherapy-induced neuropathic pain
CISP Cisplatin-treated
DMM Destabilization of the medial meniscus
eRA Early rheumatoid arthritis
HDACI Histone deacetylase inhibitors
IFA Incomplete Freund's adjuvant
IL Interleukin-treated
IP Inflammatory Pain
IPSP Incisional postsurgical pain
LLMI Lower-limb musculoskeletal injuries (via freezing)
LRA Late/established rheumatoid arthritis
MUG Microgravity-induced
MUT Genetically altered mutant
NAIVE Naïve
NGF/IL6 NGF- and IL6-treated cells
NOWS Neonatal opioid withdrawal syndrome
OA Osteoarthritis
PN Peripheral neuropathy
PNL Peripheral nerve lesion
PRL Exogenous prolactin
PSL Partial sciatic nerve ligation
SALI Saline-treated
SCD Sickle cell disease
SCI Spinal cord injury
SHAM Sham
SNC Sciatic nerve cuffing
SNI Spared nerve injury
SNL Spinal nerve ligation
SNR Sciatic nerve resection
SNT Sciatic nerve transection
STOM Oral ulcerative mucositis (stomatitis)
TAMP Tail amputation
VZV Varicella zoster virus
3ME Third molar extraction
Select All
AA
ACR
BCP
BURN
CAIA
CCD
CCI
CFA
CGN
CIPN
CISP
DMM
eRA
HDACI
IFA
IL
IP
IPSP
LLMI
lRA
MUG
MUT
NAIVE
NGF/IL6
NOWS
OA
PN
PNL
PRL
PSL
SALI
SCD
SCI
SHAM
SNC
SNI
SNL
SNR
SNT
STOM
TAMP
VZV
3ME
Search a tissue by MeSH
3. Links to Raw Data
Link to Humanized Differential Expression of Genes
Link to Humanized Differential Expression of Pathways
